• Archive of "Sickle Cell" Category

    Sickle Cell Update

    February 19, 2008 // No Comments »

    This entry is all about Sickle Cell and in particular the role that diet can have.

    There follow a sequence of Audio Recordings which you are welcome to listen to. However, i must emphasize that we are only talking about management not a cure. The cure for sickle cell is many years away and what we have focussed on over the last 2 years is all about how to manage pain and the symptoms without having to resort to Pharmaceutical Drugs. I’m not suggesting that diet can do it all but i am suggesting that a body with all the right nutrients is much better able to cope with the ravages of Sickle Cell and the evidence is clear.

    So please listen to the recordings and if you feel you’d like to leave a comment please do so by posting a comment here or on www.squidoo.com/sicklecell

    (more…)

    folic acid genetic health hemoglobin important news nutrition pioneer sickle cell disease sickle cell pain sickle crisis sicklecell transfusions Trehalose folic acid genetic health hemoglobin important news nutrition pioneer sickle cell disease sickle cell pain sickle crisis sicklecell transfusions Trehalose

    Posted in Sickle Cell

    The Greatest Tragedy of All Time

    January 15, 2008 // No Comments »

    This film was a personal response to our over reliance on the established medical treatments and it expresses some of my personal views. If you want to see more please go to website www.squidoo.com/greatesttragedye mail me


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    Trehalose - the safe sugar

    Posted in C Reactive Protein, Low GI, NIDDM, Omega 3, Sickle Cell, Trehalose, breast cancer, cancer, chemicals, cholesterol, diabetes, diet, food, glycoforms, glyconutrition, health, medicine, minerals, obesity, skin, skin care, skincare, type 2 diabetes

    Apricot Kernels - B17 - benefits

    November 16, 2007 // No Comments »

    I’ve recommended Apricot Kernels and other things as a source of B17 - wrongly called B17 as far as i can figure but that might be changing. Here is a great summary - if a little technical about B17 and what it does. We have seen some fascinating results with Sickle Cell Disease and B1, Apricot Kernels, Millet, and even Apricot Kernel Oil (cold pressed).

    Apricot Kernels (B17 – called Vitamin B17 in error)

    Apricot Kernels are the richest source of B17 (Laetrile). Ernst Krebs is the world’s leading authority on the relationship between cancer and nitrilosides, and the inventor of laetrile.

    Apricot kernels are known to prevent and cure cancer, even though the medical establishment has worked night and day and even lied to suppress it. B17 is found in most all fruit seeds such as the apple, peach, cherry, orange, nectarine and apricot. It is found in some beans and many grasses such as wheat grass. The hard wooden pit in the middle of the peach is not supposed to be thrown away. In fact, the wooden shell is strong armor protecting one of the most important foods known to man, the seed. It is one of the main courses of food in cultures such as the Navajo Indians, the Hunzas the Abkhasians and many more. Did you know that within these tribes there has never been a reported case of cancer. (And there are doctors and scientists from the U.S. living within these tribes right now studying this phenomena) We don’t need to make the seed a main course but we do need the equivalent of about seven apricots seeds per day to nearly guarantee a cancer free life. Other foods that contain vitamin B-17 are: bitter almonds, millet, wheat grass, lima beans and more. (The bitter almond tree was banned from the U.S. in 1995.) The kernel or seed contains the highest amounts of  B17.

     One of the most common nitrilosides is amygdalin. This nitriloside occurs in the kernels of seeds of practically all fruits. The seeds of apples, apricots, cherries, peaches, plums, nectarines, and the like carry this factor; often in the extraordinary concentration of 2 to 3 per cent. Since the seeds of fruits are possibly edible, it may be proper to designate the non-toxic water soluble accessory food factor or nitriloside that they contain as vitamin B-17. The presence of nitriloside in the diet produces specific physiologic effects and leaves as metabolites specific chemical compounds of a physiologically active nature. The production by a non-toxic, water-soluble accessory food factor of specific physiological effects as well as identifiable metabolites suggests the vitamin nature of the compound.

     In metabolism, nitriloside is hydrolyzed to free hydrogen cyanide, benzaldehyde or acetone and sugar. This occurs largely through the enzyme Beta-glucosidase produced by intestinal bacteria as well as by the body. The released HCN [hydrocyanide] is detoxified by the enzyme rhodanese to the relatively non-toxic thiocyanate molecule. The sugar is normally metabolized. The released benzaldehyde in the presence of oxygen is immediately oxidized to benzoic acid which is non-toxic. Thus this newly designated vitamin B-17 (nitriloside) could account for:

    1. The thiocyanates in the body fluids–blood, urine, saliva, sweat, and tears;
    2. For part of the benzoic acid (and subsequently hippuric acid); salicylic acid isomers;
    3. For the HCN that goes to the production of cyanocobalamin from hydrocobalamin, or production of vitamin B12 from provitamin B12.

    These are the physiological properties of the common nitriloside amygdalin. Before considering the possible antineoplastic activity of this vitamin B-17, let us recall that the benzoic acid arising from it has certain antirheumatic and antiseptic properties. It was rather widely used (in Germany and elsewhere) for rheumatic disease therapy prior to the advent of the ortho-hydroxy addition product of benzoic acid known as ortho-hydroxybenzoic acid or salicylic acid. It was originally obtained from beech-wood bark. As a matter of interest, the para- hydroxy isomer of benzoic acid occurs in the para hydroxybenzaldehyde aglycon (non-sugar) of the nitriloside found in the cereal millet. Millet was once more widely used in human nutrition than wheat. Wheat seed contains little or no nitriloside.

    Recall now, that thiocyanate also was once widely used, in both Germany and American medicine, as an effective agent for hypertension. Used as such, as the simple chemical, the dosage was difficult to control. Obviously, this difficulty does not arise from the thiocyanate usually produced in the body through metabolizing B-17 (nitriloside). However, chronic hypotension (the opposite of hypertension) has been reported in Nigerians who eat quantities of the nitriloside-containing manioc (cassava)–especially that of the bitter variety.

    Let us pause to reflect upon this question: Might not the rheumatic diseases as well as certain aspects of hypertension be in some cases partially related to a dietary deficiency in nitrilosides? One can hardly deny that the ingestion of a sufficient quantity of nitriloside-containing foods will metabolically yield sufficient benzoic acid and/or salicylic acid isomers to palliate rheumatic disease and certainly to decrease, however temporarily, hypertension as well as to foster the nitrilosation of provitamin B-12 to active vitamin B-12: cyanocobalamin.

    Despite all this, are we justified in suggesting that cancer itself might be another chronic metabolic disease that arises from a specific vitamin deficiency–a deficiency specifically in B-17 (nitriloside)?

    There are many chronic or metabolic diseases that challenge medicine. Many of these diseases have already been conquered. What proved to be their solution? By solution we mean both prevention and cure. What really cures really prevents. Let us think of some of these diseases that have found total prevention and hence cure. We are speaking of metabolic or non-transmissible diseases. At one time the metabolic disease known as scurvy killed hundreds of thousands of people, sometimes entire populations. This disease found total prevention and cure in the ascorbic acid or vitamin C component of fruits and vegetables. Similarly, the once fatal diseases so aptly called pernicious anaemia, pellagra, beri beri, countless neuropathies, and the like, found complete cure and prevention in specific dietary factors, that is, essential nutrients in an adequate diet.

    Let’s go a step further, almost to the border of dogmatism, to advance an axiom in medicine and biology:

    No chronic or metabolic disease has ever found cure or prevention, that is, real cure and real prevention–except through factors essential to an adequate diet and/or normal to animal economy.

    I would welcome a contradiction to this principle; but even an exception would “prove the rule.”

    Does it seem likely, therefore, that cancer will be the first exception to this generalization that to date has not had a single known exception? In my humble opinion, certainly not. But does it follow from this that B-17 (nitriloside) is the specific antineoplastic compound? Logically, by itself, alone, this conclusion that nitriloside is the specific antineoplastic compound does not follow. However, examine the brilliant laboratory studies of Dr. Dean Burk of the Department of Cytochemistry of the National Cancer Institute in Washington. I believe that in light of the experimental evidence that he has produced, you might agree that B-17 (nitriloside) is indeed the antineoplastic compound.*

    One might ask, then, whether we suggest that B-17 (nitriloside) or Laetrile is an effective cancer drug. Our reply must be: it is not a drug; it is a food.

    REFERENCES

    Baker, J.E., Rainey, D.P., Norris, D.M., and Strong, F.N., p-Hydroxybenzaldehyde and other Phenolics as Feeding Stimulants for the Smaller European Bark Bettle, Forest Sci., 14(1):91-95, 1968.
    Blum, M.S., and Woodring, J.P., Secretion of Benzaldehyde and Hydrogen Cyanide by the Millipede Pachydemus crassicutus (Wood), Science, 158: 512-513, 1962.
    Briese, R.R., and Couch, J.F., Preservation of Cyanogenetic Plants for Chemical Analysis, J.Agr.Research, 57(2): 81-107, 1937.
    Brown, W.E., Wood, C.D., and Smith, A.N., Sodium Cyanide as a Cancer Chemotherapeutic Agent — Laboratory and Clinical Studies, Am.J.Obst. & Gynec., 80: 907-918, 1960.
    Browne, J.G., Progress Report on the Work Done on the Hydrocyanic Acid Content of California Grown Lima Beans, Univ. Calif. Coll. of Agr., Agr. Exptl. Station, Project No. 521, p. 770 et seq., June 17, 1932.
    Brioux, and Jones, E., The Production of Cyanogenetic Glycosides by Linseed: Measurement of HCN Production, Ann. Agron., 8(4): 468-480, 1932.
    Chappel, C., Toxicity Studies on Amygdalin, McNaughton Foundation, Montreal, Canada, 1967, p.2.
    Charlton, J., The Selection of Burma Beans for Low Hydrocyanic Acid Content, Memoirs Dept. Agr. India Chemical Series, 9(1), 1926-1928.
    Dedolph, R.R., and Hamilton, R.A., The Bitterness Problem in Some Seedling Macadamias (Due to amygdalin — ed.), Hawaii Farm. Sci., 8(1): 7-8, 1959.
    Delga, J., Mizoula, J., Veverka, B., and Bon, R., Studies on the Treatment of Cyanide Intoxication by Hydroxycobalamin (Provitamin B-12), Ann. Pharmaceut., 19(12): 740-752, 1961.
    Dillemann, G., Hydrocyanic Acid in Hybrids of the Pear with the Quince, Bull. Museum Natl. Hist. Nat., 18: 465-467, 1946.
    Doak, B.W., Cyanoglucosides in White Clover, New Zealand J.Agr., 51: 159-162, 1935.
    Domingues, J.B., Hydrocyanic Acid in Shoots of Dendrocalamus giganteus (Bamboo), An.Fac.Farm., E. Odontal Univ., Sao Paulo, 13: 169-171, 1955-1956.
    Dunstan, W.R., Henry, T.A., and Auld, S.J.M., Cyanogenesis
    IV. Occurrence of Phaseolunatin in Common Flax
    V. Occurrence of Phaseolunatin in Cassava,Proc.Roy.Soc., 1906, 78B, 145-158.
    Dunstan, W.R., and Henry, T.A., and Auld, S.J.M., Cyanogenesis in Plants
    II. The Great Millet, Sorghum vulgare, Phil.Trans.Roy.Soc.,199A: 399-410, 1902.
    Dunstan, W.R., Henry, T.A., and Auld, S.J.M., Cyanogenesis
    VI. Phaseolunatin and the Associated Enzymes in Flax, Cassava, and the Lima Bean, Proc.Roy.Soc., 79B: 315-322, 1907.
    Ekpechi, O.L., Dimitriadoo, A., and Fraser, R., Goitrogentic Activity of Cassava (A Staple Nigerian Food), Nature, 5041: 1137, June 11, 1966.
    Festenstein, G.U., Substrates for Rumen Beta-Glucosidase, Biochem. J., 70(1): 49-51, 1958.
    Flux, D.S., Butler, G.W., Johnson, J.M., Glenday, A.C., and Petersen, G.B., Goitrogenic Effects of White Clover, New Zealand J.of Sci. and Tech., 38(A): 88-102, 1956.
    Flux, D.S., Butler, G.W., Rae, A.L., and Brougham, R.W., Relationship between Levels of Iodine and Cyanogenetic Glucoside in Pasture and the Performance of Sheep, J.Agric.Soc., 55(2): 191-196, 1960.
    Golse, J., New Method for the Determination of Hydrocyanic Acid and Benzaldehyde in Cherry Brandy, J.Phar.Chim., 12:44-65, 1915.
    Greshoff, M., The Distribution of Prussic Acid (HCN) in the Vegetable Kingdom, Report Brit.Assn., 138-144, 1906.
    Guignard, L., The Development of Cyanogenetic Glucosides During the Germination of Plants, Compt.rend., 147: 1023-1038, 1908.
    Guignard, L., The Presence of Cyanide-Yielding Compounds in the Elderberry, Compt.rend., 141: 16-20, 1905.
    Herissey, H., The Cyanogenetic Glycoside Prulsurasin Crystallized from the Leaves of the Cherry Laurel, Compt.rend., 141: 959-961, 1905.
    James, M.B., Fleming, J.W., and Bailey, L.F., Cyanide as a Growth-Inhibiting Substance in Extracts of Peach Leaves, Proc.Amer.Soc.Hort. Sci., 69: 152-157, 1957.
    Jones, M.B., Seasonal Trend of Cyanide in Peach Leaves and Flower Buds and Its Possible Relation to the Rest Period.Proc. amer.Soc.Hort.Sci., 77: 117-120, 1961.[nee Jones?, rsc]
    Liebig, J., and Wohler, F., The Composition of Bitter Almonds,Annalen, 22(1): 1-24, 1837.
    Liebig, J., and Wohler, F., Formation of the Oil of Bitter Almonds, Ann.Chim.Phys., 64: 185-209, 1837.
    Luh, B.S., and Pinochet, M.F., Spectrophotometric Determination of Hydrogen Cyanide in Canned Apricots, Cherries and Prunes, Food Research, 24: 423-427, 1950.
    Martin, J.H., Couch, J.F., and Briese, R.R., Hydrocyanic Acid Content of Different Parts of the Sorghum Plant, Jour.Amer.Soc.Agron., 30(9): 725-734, 1938.
    Michajlovski, M., Stukovsky, R., and Nemeth, S., Effects of Feed Composition on the Thiocyanate Content of Cow Milk, Biologica(Broteslavia), 16: 459-468, 1961.
    Monekosso, G.L., and Wilson, J., Plasma Thyocyanate and Vitamin B-12 in Nigerian Patients with Neurological Disease, Lancet, No. 7446: 1062-1064, 1966.
    McIlroy, “The Plant Glycosides,” Edward Arnold & Co., London, 1951, pp.21-22.
    Oke, O.L., Chemical Studies of Some Nigerian Vegetables, Exp.Agr., 1(2): 125-129, 1965.
    Osborne, D., Solving the Riddle of Wetherhill Mesa, Natl.Geo.Mag., 125(2): 155-194, 1964.
    Perry, I.H., The Effect of Prolonged Cyanide Treatment on Body and Tumor Growth in Rats, Am.J.Cancer, 25: 592-[ff.],1935.
    Pobiondek-Eabini, R., The Hydrogen Cyanide Content of Millet, Arch.Tiernarh., 2/3, 71-80, 1951.
    Pjoan, M., Cyanide Poisoning from Choke Berry Seed, Am.J.Med.Sci., 204: 350-553, 1942.
    Rabati, J., Biochical Study of the Peach Tree, The Presence of Amygdonitrile Glucoside, Bull.Soc.Chim.Biol., 15: 385-395, 1933.
    Schroder, J., and Damman, H., Studies of the Amount of Hydrocyanic Acid Obtained from Different Millets, Chem.Ztg., 35: 1436-7 (Chem.Abst. 62 1327).
    Stebbins, R.C., Lizards Killed by Millipede (Through HCN-benzaldehyde emission from latter, ed.), Amer.Midland Nat., 32(3); 771-778, 1944.
    Weiss, M., Hydrocyanic Acid in Apple Embryos, Flora, 149(3): 386-395, 1960.
    Wokes, F., and Willimott, S.G., The Determination of Cyanide in Seeds, J.Pharm. & Pharmacol., 3: 905-917, 1951.
    Worth, F.J., A Note on the Hydrocyanic Acid Content in Burma Beans, Memoirs Dept. Agi. India Chem.Series, 7(1), 1928 (cf paper by Browne, J.G.).

     

    Posted in Nitric Oxide, Sickle Cell, Vitamins, cancer, chemicals, diet, heart, hypotension, medicine

    6 Helpful Ideas To Stay Healthy

    September 25, 2007 // No Comments »

    6 Simple ideas to promote health

    Fed up with hearing about the plight of our declining health. Follow these 6 simple principles and you can help but lose fat and improve your health over time.

    Have a great day Paul Barton www.sugars4life.com


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    1. Whenever possible, eat foods that are in their natural state.

    (Note: This rule does not apply to meats and other foods that are dangerous to eat raw.) In this rule, reference is made to a food like carrots. What is the natural state of a carrot? Raw. When carrots are eaten raw, they are safe and natural-the way they were designed to be eaten. Raw carrots also fit the second rule-to eat foods that are harder to digest. Carrots also fit the third rule since they are high in fiber. Raw carrots have an index number of 35 (low-glycemic), but cooked carrots (not in their natural state) have an
    index of 65 (moderately glycemic).

    2. Eat foods that are harder to digest.

    The harder a food is to digest, the lower-glycemic it usually is. The harder the food is to digest, the longer ittakes to convert to sugars. This longer process minimizes insulin reactions. You can then maximize your conversion of food to energy and minimize the amount of food converting to fat. For example, cooked carrots are very easy to digest, so their index is much higher than raw carrots.

    3. Eat foods that are high in fiber.

    Fiber ranges from hard to digest to impossible to digest. Impossible to digest is actually good for humans. It not only helps with a feeling of fullness, but also helps to clean our colons-which is essential for good health. The higher the fiber, typically the more absorbent it is for fats. The slower the digestive process isfor a specific food, generally, the lower the glycemic index will be for that food. A good example is bread. Highly refined white bread’s fiber is so broken down and easy to digest that it is virtually useless for colon health. It is not in its natural state (Rule No.1), and it is white (Rule No. 6). However, whole grain bread with seeds is as close as bread gets to the natural state of grain. Depending on the grain and the seeds, it could be low-or moderately glycemic, but not high-glycemic. So you can have bread, but not highly refined flours and breads that are high-glycemic.

    4. Time your food intake.

    It is very important to your overall health-but particularly important to achieving a lean body-to keep your blood sugar balanced. Skipping meals may save calories, but will eventually backfire since your body will perceive a state of starvation and reduce the rate at which you convert your stored fats. Snacking is fine (even helpful) if it is with the right foods. Snacking helps keep your blood sugar balanced this in turn helps control appetite and maintain your ability to convert stored fat as energy. It would be ideal if we could get every one to snack only on fresh fruits or vegetables that are low-glycemic, such as peaches or celery. But this isn’t always convenient, so here is one practical (and tasty!) suggestion: A dozen almonds in their natural state eaten every two hours between meals should help the average person maintain a reasonable level of blood sugar.

    5. Avoid white foods.

    There are, of course, exceptions to every rule if you look hard enough. In general, white foods tend to be high-glycemic. White potatoes are the highest (85-98) on the glycemic index. They are a starchy complex, and those starches convert to glucose rapidly. Additionally, they are very easy to digest (Rule No. 2) and contain very little fiber (Rule No. 3).

    6. Do not use artificial sweeteners.

    There is preliminary evidence that artificial sweeteners may in fact slow the fat-burning process by confusing the normal chemical signals to the brain. An healthy alternative and actually beneficial sugar is Trehalose. These signals are normally associated with sweet tastes. There is also an increasing body of evidence that indicates some artificial sweeteners may have harmful effects on the human body.

    Learn more about how plant sugars are transforming the world view of health. See what one specific plant sugar, Trehalose, can do to help diabetes and neurological issues like MS, Parkinsons, Huntingtons, Alzheimers.

    Posted in Sickle Cell, Trehalose, diabetes, diet, food, glyconutrition, health

    Nitric Oxide - and Health

    September 24, 2007 // 2 Comments »

    With our work on Sickle Cell Disease over the last few months we’ve been trialling a compound that is known to produce Nitric Oxide. the initial results we’ve seen are very encouraging - like reducing sickle cell crisis pain to manageable levels within 15 minutes. This article is one that was one i came across today which supports the view that NO or Nitric Oxide is very helpful in a number of health issues.

    If you’d like to know what compound we are using and where to get it please e mail me paul@sugars4life.com

    Nitric oxide:From menace to marvel of the decade

    A briefing document prepared for the Royal Society and Association of British Science Writers

    Pearce Wright


    May 1996

    Nitric oxide: From menace to marvel of the decade

    Summary Research papers continue to flood the scientific journals with insights into the biological activity and potential clinical uses of nitric oxide (NO): a gas controlling a seemingly limitless range of functions in the body. Each revelation adds to nitric oxide’s already lengthy resume in controlling the circulation of the blood, and regulating activities of the brain, lungs, liver, kidneys, stomach, gut, genitals and other organs.

    The molecule governs blood pressure, through a recently recognised process that contradicts textbook wisdom. It causes penile erections by dilating blood vessels, and controls the action of almost every orifice from swallowing to defecation. The immune system uses nitric oxide in fighting viral, bacterial and parasitic infections, and tumours. Nitric oxide transmits messages between nerve cells and is associated with the processes of learning, memory, sleeping, feeling pain, and, probably, depression. It is a mediator in inflammation and rheumatism.

    Clinically, newborn babies with breathing problems are getting relief by an experimental inhalation treatment developed from this new understanding. A novel class of drugs that block the production of nitric oxide is being assessed as a possible treatment for septic shock. Drugs that liberate or enhance the action of nitric oxide may be useful in the treatment of pulmonary hypertension, and could prevent the formation of blood clots and counteract impotence. Animal experiments show how to manipulate nitric oxide production to stop the development of arthritis and kidney disease.

    In the longer term, drugs that alter the amount or activity of nitric oxide might help protect the brain in conditions such as stroke, Alzheimers and Parkinsons disease. (more…)

    Posted in Nitric Oxide, Sickle Cell, cancer, diabetes, diet, food, health, heart